effect of rosuvastatin on serum ctni, cys-c, hcy and myocardial enzyme, inflammatory cytokines in acute myocardial infarction with pci surgery
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2016
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Abstract
Objective: To observe the effect of rosuvastatin on serum cTNI, Cys-C, Hcy and myocardial
enzyme, inflammatory factors in acute myocardial infarction with percutaneous coronary
intervention (PCI) surgery. Methods: A total of 80 patients with acute myocardial infarction
were randomly divided into control group (40 cases) and experiment group (40 cases), the
control group were given atorvastatin on the basis of basic therapy, and the experiment group
were given rosuvastatin on the basis of basic therapy. The change of serum cTNI, Cys-C, Hcy,
LDH, CK, CK-MB, IL-1β, IL-6, IL-17 in 24 hours and 8 weeks after PCI surgery of two
groups were compared. Results: The serum cTNI, Cys-C, Hcy, LDH, CK, CK-MB, IL-1β,
IL-6, IL-17 in 8 weeks after PCI surgery of two groups were significantly lower than that of
24 hours after PCI surgery (P<0.05). The serum cTNI, Cys-C, Hcy, LDH, CK, CK-MB, IL-1
β, IL-6, IL-17 in 8 weeks after PCI surgery of experiment group were significantly lower
than that of 8 weeks in control group (P<0.05). Conclusions: Rosuvastatin can significantly
decrease the myocardial enzyme, inflammatory cytokines in acute myocardial infarction with
PCI surgery. It plays an important role in protecting the heart function, reversing myocardial
damage, and inhibiting cardiac remodeling.
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| Reference Key |
shen2016journaleffect
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|---|---|
| Authors | ;Na Shen;Zeng-Xin Yang |
| Journal | journal of communications |
| Year | 2016 |
| DOI |
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