management of skin toxicity related to the use of imatinib mesylate (sti571, glivec™) for advanced stage gastrointestinal stromal tumours

Clicks: 221
ID: 136837
2005
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Abstract
Skin toxicity is a common side-effect of treatment with imatinib mesylate (STI571, Glivec™) in advanced gastrointestinal stromal tumours (GIST) and chronic myeloid leukaemia. The optimal duration of treatment with imatinib mesylate in GIST has not yet been established, as durable remissions have been observed in patients. It is, therefore, important to develop strategies to deal with common side-effects of what may be a long-term treatment. Here we report the case of a patient with advanced GIST who developed a cutaneous drug reaction secondary to imatinib mesylate and the various management options that may be employed depending upon the severity of the toxicity. The case and literature are discussed.
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scott2005sarcomamanagement Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Lucy C. Scott;Jeff D. White;Robin Reid;Fiona Cowie
Journal the journal of physiology
Year 2005
DOI
10.1080/13577140500349717
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