dietary fat, sugar consumption, and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction

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ID: 132581
2017
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Abstract
Heart failure with preserved ejection fraction (HFpEF) is associated with obesity and, indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely unknown. In this study, the authors showed that in obese HFpEF patients, consumption of unsaturated fatty acids (UFA), was associated with better cardiorespiratory fitness, and UFA consumption correlated with better diastolic function and with greater fat-free mass. Similarly, mice fed with a high-fat diet rich in UFA and low in sugars had preserved myocardial function and reduced weight gain. Randomized clinical trials increasing dietary UFA consumption and reducing sugar consumption are warranted to confirm and expand our findings.
Reference Key
ms2017jacc:dietary Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Salvatore Carbone, MS;Justin M. Canada, MS, RCEP;Leo F. Buckley, PharmD;Cory R. Trankle, MD;Hayley E. Billingsley, RD;Dave L. Dixon, PharmD;Adolfo G. Mauro, MS;Sofanit Dessie, MD;Dinesh Kadariya, MD;Eleonora Mezzaroma, PhD;Raffaella Buzzetti, MD;Ross Arena, PhD;Benjamin W. Van Tassell, PharmD;Stefano Toldo, PhD;Antonio Abbate, MD, PhD
Journal journal of nuclear materials
Year 2017
DOI
10.1016/j.jacbts.2017.06.009
URL
http://www.sciencedirect.com/science/article/pii/S2452302X17302012
Keywords
obesity diet body composition heart failure with preserved ejection fraction unsaturated fatty acidsdiseases of the circulatory (cardiovascular) system

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