alopecia areata and vitiligo as primary presentations in a young male with human immunodeficiency virus

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ID: 130328
2014
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Abstract
A 26-year-old Chinese male consulted with the team regarding his alopecia areata and vitiligo for which previous treatment was ineffective. The patient, a homosexual man, denied having a history of drug abuse and of blood transfusion. No member of his family had vitiligo or alopecia. Laboratory studies revealed that the serum for anti-human immunodeficiency virus (HIV) antibody was positive. The patient′s CD4 lymphocyte count and CD4/CD8 ratio were both strikingly low (20 cells/mL and 0.04), but no other complaints or opportunistic infections were reported. One month after antiretroviral therapy, the patient′s alopecia areata dramatically improved, but no evident improvement in his vitiligo was found. This case is a very rare case of alopecia areata and vitiligo associated with HIV infection that might be attributed to the generation and maintenance of self-reactive CD8+ T-cells due to chronic immune activation with progressive immune exhaustion in HIV infection.
Reference Key
xuan2014indianalopecia Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Li Xuan;Yang Baohua;Baohua Lan
Journal heterocycles
Year 2014
DOI
10.4103/0019-5154.127710
URL
http://www.e-ijd.org/article.asp?issn=0019-5154;year=2014;volume=59;issue=2;spage=209;epage=209;aulast=Xuan
Keywords
human immunodeficiency virus alopecia areata acquired immune deficiency syndrome

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