distribution of class i integron among isolates of acinetobacter baumannii recoverd from burn patients

Background: Acinetobacter baumannii, is an important opportunistic pathogens   responsible   for   nosocomial   infections.   The   aim   of   this experiment  was  to  determine  prevalence  of  Class  I  Integron  in  A. baumannii strains isolated from burn patients in Mottahari Hospital and the drug susceptibility pattern.

Methods: There were 69 Acinetobacter isolates, 68 (98.5%) were identified as A. baumannii. Antimicrobial susceptibility of these isolates were determined by a disk diffusion method. PCR assay for detection of blaOXA-

51 like gene (for identity confirmation) and intI was performed.

Results:  The  most  effective  antibiotic  for  treating  A.  baumannii  was colistin, followed by tetracyclin and tobramycin. The presence of Integron class  I  was  detected  in  14.49%  of  isolates.  ESBL  and  carbapenemase production were observed in 10% and 24.6% of isolates, respectively. Conclusion: Due to the high resistance of strains lacking Integron I, the findings are although class I integrons are disseminated among clinical isolates  of  A.  baumannii,  at  present  research,  they  they  do  not  play important role in dissemination of antibiotic resistance genes in Mottahari

Hospital in Tehran, Iran.