a clinical perspective on the role of chronic inflammation in gastrointestinal cancer

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ID: 128773
2014
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Abstract
Sebastian Rasch, Hana Algül II Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany Abstract: Chronic inflammation has been identified as an important risk factor for the development of malignancy, and knowledge about its molecular and cellular mechanisms is increasing. Several chronic inflammatory diseases of the gastrointestinal tract are important as risk factors for malignancy and have been studied in detail. In this review, we summarize important molecular mechanisms in chronic inflammation and highlight established and potential links between chronic inflammation and gastrointestinal cancer. In addition, we present the role of chronic inflammation in numerous tumors within the gastrointestinal tract as well as the relevant pathways or epidemiologic observations linking the pathogenesis of these tumors to inflammation. Keywords: inflammation, immune response, carcinogenesis, gastrointestinal cancer, risk factor
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s2014clinicala Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Rasch S;Algül H
Journal journal of biosciences
Year 2014
DOI
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URL
http://www.dovepress.com/a-clinical-perspective-on-the-role-of-chronic-inflammation-in-gastroin-peer-reviewed-article-CEG
Keywords
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