Antiangiogenic phenylpropanoid glycosides from Gynura cusimbua.

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ID: 125668
2019
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Abstract
A new phenylpropanoid glycoside, named α-L-rhamnopyranosyl-(1↔2)-β-D-[4″-(8E)-7-(3,4-dihydroxyphenyl)-8-propenoate, 1″-O-(7S)-7-(3,4-dihydroxyphenyl)-7-methoxy-ethyl]-glucopyranoside (1), together with nine known compounds (2-10) were isolated from the active fraction (n-Butanol fraction) of Gynura cusimbua for the first time. The known compounds (2-10) were identified as phenylpropanoid glycosides on the basis of extensive spectral data and references. The antiangiogenic activities of compounds (1-10) were evaluated by MTT assay on HUVECs and wild-type zebrafish in vivo model assay. As a result, compounds 1, 6, 7, 8 and 10 exhibited certain antiangiogenic activities.
Reference Key
ma2019antiangiogenicnatural Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ma, Qinge;Wei, Rongrui;Zhou, Bin;Sang, Zhipei;Liu, Wenmin;Cao, Zhongling;
Journal Natural product research
Year 2019
DOI
10.1080/14786419.2017.1389931
URL
Keywords
antiangiogenic activities phenylpropanoid glycosides

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