Hepatoprotective and neuroprotective flavanes from the fruits of Ulmus pumila L. (Ulmaceae).

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ID: 125660
2019
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Abstract
Phytochemical study of the EtOAc fraction (active extract) of the fruits of Ulmus pumila L. resulted in the isolation of thirteen flavane derivatives, and they were identified by their precise spectral data and literature. All the compounds (1-13) were obtained from the fruits of U. pumila L. for the first time. Meanwhile, the compounds (1-13) were assayed for their hepatoprotective and neuroprotective activities, respectively. Compounds 1, 2, 5, 7 and 8 (10μM) exhibited remarkable hepatoprotective activities, and compounds 9, 10, and 13 showed significant neuroprotective activities with IC50 values of 4.08, 5.34, and 2.02μM, respectively.
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ma2019hepatoprotectivepakistan Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ma, Qinge;Wei, Rongrui;Shang, Dongli;Sang, Zhipei;Liu, Wenmin;Cao, Zhongling;
Journal pakistan journal of pharmaceutical sciences
Year 2019
DOI
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Keywords
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