Lactobacillus gastricus BTM 7 prevents intestinal colonization by biofilm forming Cronobacter sakazakii in Caenorhabditis elegans model host.

Clicks: 399
ID: 121424
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #8 of 260 articles by views in antonie van leeuwenhoek

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 260 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The study reports protective role of potential probiotic cultures against infection by biofilm forming Cronobacter sakazakii in Caenorhabditis elegans model system. Among the fifteen indigenous potential probiotics, the cell free supernatant of Lactobacillus gastricus BTM7 possessed highest antimicrobial action and biofilm inhibition against C. sakazakii. The competitive exclusion assays revealed that preconditioning with probiotics resulted in increased mean life span of the nematode to 12-13 days as compared to 5-6 days when the pathogen was administered alone. Enhanced expression of the marker genes (pmk-1, daf-16 and skn-1) was observed during the administration of probiotic cultures. The highest expression of pmk-1 (2.5 folds) was observed with administration of L. gastricus BTM7. The principal component analysis on selected variables revealed that L. gastricus BTM7 has the potential to limit the infection of C. sakazakii in C. elegans and enhance the expression of key genes involved in extending life span of the worm.
Reference Key
kavita2020lactobacillusantonie Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kavita, Sharma;Pooranachithra, Murugesan;Singh, Niharika;Prasanth, Mani Iyer;Balamurugan, Krishnaswamy;Goel, Gunjan;
Journal antonie van leeuwenhoek
Year 2020
DOI
10.1007/s10482-020-01466-7
URL
Keywords
Antimicrobial activity biofilm caenorhabditis elegans probiotics cronobacter sakazakii

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.