Pharmacodynamics of levofloxacin and ciprofloxacin in a murine pneumonia model: peak concentration/MIC versus area under the curve/MIC ratios

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2003
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Abstract
During the last decade some studies have shown that the area under the curve (AUC)/MIC ratio is the pharmacodynamic index that best predicts the efficacies of quinolones, while other studies suggest that the predictive value of the peak concentration/MIC (peak/MIC) ratio is superior to the AUC/MIC r …
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Authors Scaglione F;Mouton JW;Mattina R;Fraschini F;;
Journal Antimicrobial agents and chemotherapy
Year 2003
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