Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome

Clicks: 352
ID: 119963
2007
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Abstract
Prenatal androgenization in female rhesus monkeys induces adiposity-dependent visceral fat accumulation, and late gestation androgenization causes increased total body and non-visceral fat mass. Early gestation androgenization induces visceral fat-dependent hyperinsulinemia. The relationship between …
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Authors Bruns CM;Baum ST;Colman RJ;Dumesic DA;Eisner JR;Jensen MD;Whigham LD;Abbott DH;;
Journal international journal of obesity (2005)
Year 2007
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/17471299
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine pregnancy treatment outcome research support female N.I.H. Extramural Tomography Insulin Resistance* d h abbott absorptiometry photon body composition / physiology x-ray computed case-control studies macaca mulatta prenatal exposure delayed effects* polycystic ovary syndrome / complications* pmid:17471299 pmc2597033 doi:10.1038/sj.ijo.0803638 c m bruns s t baum androgens / administration & dosage androgens / adverse effects* body composition / drug effects* body fat distribution* glucose tolerance test / methods Epidemiology public health internal medicine metabolic diseases health promotion and disease prevention general medicine/public health Epidemiology public health internal medicine metabolic diseases health promotion and disease prevention general medicine/public health

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