Cerebral atrophy in AIDS: a stereological study

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ID: 118650
1970
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Abstract
Stereological estimates of mean volumes, surface areas, and cortical thicknesses were obtained on formalin-fixed brains from 19 men with AIDS and 19 controls. Volumes of neocortex, white matter, central brain nuclei, ventricles and archicortex were estimated using point counting and Cavalieri's unbiased principle for volume estimation. In AIDS, the mean volume of neocortex was reduced by 11%, and that of the central brain nuclei by 18%. Mean ventricular volume was increased by 55%. Mean neocortical thickness was reduced by 12%. The mean volume of white matter was reduced by 13%. The findings in 6 clinically demented AIDS patients were not statistically different from the rest of the group.
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oster1970actacerebral Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors S. Oster;P. Christoffersen;H. J. G. Gundersen;J. O. Nielsen;B. Pakkenberg;C. Pedersen;S. Oster;P. Christoffersen;H. J. G. Gundersen;J. O. Nielsen;B. Pakkenberg;C. Pedersen;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00334671
URL
https://link.springer.com/article/10.1007/BF00334671
Keywords
pathology neurosciences

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