A multicenter, double-blind, placebo-controlled trial comparing piperacillin-tazobactam with and without amikacin as empiric therapy for febrile neutropenia

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ID: 118063
2001
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Ranked #60 of 562 articles by views in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

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Abstract
In a prospective, multicenter, double-blind, randomized clinical trial, we compared the efficacy of piperacillin-tazobactam (4.5 g 3 times daily intravenously) plus placebo versus piperacillin-tazobactam plus amikacin (7.5 mg/kg twice daily intravenously) for the treatment of 760 febrile, adult pati …
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Authors Del Favero A;Menichetti F;Martino P;Bucaneve G;Micozzi A;Gentile G;Furno P;Russo D;D'Antonio D;Ricci P;Martino B;Mandelli F; ;;
Journal Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11565068
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male adolescent aged middle aged Comparative Study Prospective Studies Clinical Trial Randomized Controlled Trial Double-Blind Method Multicenter Study drug therapy neutropenia / complications* neutropenia / chemically induced fever / etiology* bacterial infections / drug therapy* anti-bacterial agents / therapeutic use* combination / therapeutic use* pmid:11565068 doi:10.1086/322646 a del favero f menichetti gruppo italiano malattie ematologiche dell'adulto (gimema) infection program amikacin / therapeutic use* bacterial infections / physiopathology penicillanic acid / analogs & derivatives penicillanic acid / therapeutic use* piperacillin / therapeutic use* piperacillin tazobactam drug combination

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