Timing of prenatal androgen excess determines differential impairment in insulin secretion and action in adult female rhesus monkeys

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2000
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Abstract
This study determined whether timing of prenatal androgen excess resulted in differential impairment of insulin-glucose homeostasis in adult female rhesus monkeys. Ten female rhesus monkeys exposed to testosterone propionate starting on gestational day 40 (early treated), 9 females exposed to testos …
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Authors Eisner JR;Dumesic DA;Kemnitz JW;Abbott DH;;
Journal the journal of clinical endocrinology and metabolism
Year 2000
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10720063
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine pregnancy research support non-u.s. gov't u.s. gov't female gestational age* P.H.S. d a dumesic d h abbott body mass index Blood Glucose / metabolism macaca mulatta testosterone / pharmacology* prenatal exposure delayed effects* glucose tolerance test insulin / blood insulin secretion insulin / metabolism* pmid:10720063 doi:10.1210/jcem.85.3.6453 j r eisner insulin / physiology* islets of langerhans / drug effects islets of langerhans / physiology ovulation / physiology

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