Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells
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ID: 117788
2018
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Abstract
High concentrations of glutamate may mediate neuronal cell apoptosis by increasing intracellular reactive oxygen species (ROS) levels. Peroxiredoxin V (Prx V), a member of the Prx family, serves crucial roles in protecting cells from oxidative stress. The present study investigated the regulatory ef …
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gn2018molecularknockdown
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| Authors | Shen GN;Liu L;Feng L;Jin Y;Jin MH;Han YH;Jin CH;Jin YZ;Lee DS;Kwon TH;Cui YD;Sun HN;; |
| Journal | molecular medicine reports |
| Year | 2018 |
| DOI |
DOI not found
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| URL | |
| Keywords |
Tumor
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
reactive oxygen species / metabolism
Apoptosis / drug effects
cell line
hu-nan sun
apoptosis / genetics*
peroxiredoxins / genetics*
extracellular signal-regulated map kinases / metabolism
gui-nan shen
pmid:29620243
doi:10.3892/mmr.2018.8826
lei liu
apoptosis inducing factor / metabolism
gene knockout techniques
glutamic acid / metabolism*
glutamic acid / pharmacology
pyramidal cells / drug effects
pyramidal cells / metabolism*
|
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