Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells

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ID: 117788
2018
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Abstract
High concentrations of glutamate may mediate neuronal cell apoptosis by increasing intracellular reactive oxygen species (ROS) levels. Peroxiredoxin V (Prx V), a member of the Prx family, serves crucial roles in protecting cells from oxidative stress. The present study investigated the regulatory ef …
Reference Key
gn2018molecularknockdown Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shen GN;Liu L;Feng L;Jin Y;Jin MH;Han YH;Jin CH;Jin YZ;Lee DS;Kwon TH;Cui YD;Sun HN;;
Journal molecular medicine reports
Year 2018
DOI
DOI not found
URL
https://www.pubmed.gov/29620243/
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine reactive oxygen species / metabolism Apoptosis / drug effects cell line hu-nan sun apoptosis / genetics* peroxiredoxins / genetics* extracellular signal-regulated map kinases / metabolism gui-nan shen pmid:29620243 doi:10.3892/mmr.2018.8826 lei liu apoptosis inducing factor / metabolism gene knockout techniques glutamic acid / metabolism* glutamic acid / pharmacology pyramidal cells / drug effects pyramidal cells / metabolism*

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