Inhibitory effect of pyridobenzazoles on virus replication in vitro

Clicks: 312
ID: 117510
1995
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Abstract
Twelve species of pyridobenzazoles and pyrimidobenzimidazole were examined as inhibitors of the replication of respiratory syncytial virus (RSV) in HeLa cells. From the pyridobenzazoles studied, 2-benzamido-4-cyano-1-oxo-1H,5H-pyrido[1,2-alpha]benzimidazol emerged as a potent inhibitor of the RSV. B …
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Authors Chiba T;Shigeta S;Numazaki Y;;
Journal biological & pharmaceutical bulletin
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8535400
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Cells Cultured respiratory syncytial viruses / drug effects* antiviral agents / pharmacology* hela cells influenza a virus / drug effects* influenza a virus / physiology simplexvirus / physiology respiratory syncytial viruses / physiology cytopathogenic effect viral / drug effects s shigeta pmid:8535400 doi:10.1248/bpb.18.1081 t chiba y numazaki benzimidazoles / pharmacology* simplexvirus / drug effects* virus replication / drug effects*

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