Experimental Chandipura virus infection in mice

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ID: 117501
1970
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Abstract
Chandipura virus was inoculated intraperitoneally into 9-day old mice. Rising viral titers were detected in blood, skeletal muscle and viscera, beginning 3 to 6 h post-inoculation. Significant quantities of virus were initially noted in the brain at 24 h, and titers in that region rose precipitously during the succeeding 72 h. Detectable clinical signs, including neurologic dysfunctions began 48 h post-inoculation. Death was common at 72 and 96 h. The most significant and consistently observed lesions were in the central nervous system and included necrosis of neurons and ependymal cells.
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jortner1970actaexperimental Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Bernard S. Jortner;Pravin N. Bhatt;Gilbert B. Solitare;Bernard S. Jortner;Pravin N. Bhatt;Gilbert B. Solitare;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00687461
URL
https://link.springer.com/article/10.1007/BF00687461
Keywords
pathology neurosciences

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