Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group

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ID: 117494
1996
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Abstract
The combination of lamivudine and zidovudine results in a potent and sustained antiviral effect in antiretroviral-naive patients that is superior to that observed with zidovudine monotherapy.
Reference Key
c1996jamasafety Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Katlama C;Ingrand D;Loveday C;Clumeck N;Mallolas J;Staszewski S;Johnson M;Hill AM;Pearce G;McDade H;;
Journal JAMA
Year 1996
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8656503
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male middle aged Drug Administration Schedule Comparative Study Clinical Trial Randomized Controlled Trial Double-Blind Method Multicenter Study Genotype drug resistance viral / blood drug therapy combination antiviral agents / administration & dosage antiviral agents / therapeutic use* cd4 lymphocyte count microbial / genetics hiv infections / immunology hiv infections / drug therapy* pmid:8656503 c katlama d ingrand h mcdade hiv-1* / drug effects hiv-1* / genetics lamivudine reverse transcriptase inhibitors / administration & dosage reverse transcriptase inhibitors / therapeutic use* zalcitabine / administration & dosage zalcitabine / analogs & derivatives* zalcitabine / therapeutic use zidovudine / administration & dosage zidovudine / therapeutic use*

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