Freeze-fracture studies of gap junctions of normal and neoplastic astrocytes
Clicks: 250
ID: 117080
1970
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
30.0
/100
250 views
38 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #58 of 438 articles by views in acta neuropathologica
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 438 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Gap junctions of normal and neoplastic astrocytes were studied by the use of freeze-fracture or-etching technique. The gap junctions between normal astrocytes generally revealed a structure composed of small particles on fracture face A and associated pits on fracture face B. The particles and pits had presumably a complementary correlation: however, the pits were usually more regularly oriented—often in hexagonal array—than the particles. In the astrocytoma, the gap junctions were abundant and the pits were occasionally in tetragonal array. In the glioblastoma multiforme, the number of gap junctions was markedly decreased and the space between the particles sometimes increased, indicating a loose arrangement of the particles. The gap junctions in normal and neoplastic astrocytes demonstrated discontinuous macular plaques and did not exhibit continuous zones around the astrocytes. There was no evidence of tight junction in the fracture replicas of astrocytes. The present study might suggest that the malignancy of neoplastic astrocytes is represented by the decrease of the gap junction or by the loose orientation of the particles in the gap junction.
| Reference Key |
tani1970actafreeze-fracture
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Eiichi Tani;Mitsugu Nishiura;Noboru Higashi;Eiichi Tani;Mitsugu Nishiura;Noboru Higashi; |
| Journal | acta neuropathologica |
| Year | 1970 |
| DOI |
doi:10.1007/BF00697748
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.