Empirical antibiotic choice for the seriously ill patient: are minimization of selection of resistant organisms and maximization of individual outcome mutually exclusive?

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2003
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Abstract
Mortality related to serious infections in intensive care units (ICUs) is highest if empirical therapy is not active against the organism causing the infection. However, excessive empirical therapy undoubtedly contributes to bacterial resistance to antibiotics, in turn potentially contributing to po …
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Authors Paterson DL;Rice LB;;
Journal Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Year 2003
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