Evaluation of a PCR assay for detection of Streptococcus pneumoniae in respiratory and nonrespiratory samples from adults with community-acquired pneumonia

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2003
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Abstract
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia, but it is undoubtedly underdiagnosed. We used a nested PCR assay (targeting the pneumolysin gene) to detect S. pneumoniae DNA in multiple sample types from 474 adults with community-acquired pneumonia and 183 control …
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Authors Murdoch DR;Anderson TP;Beynon KA;Chua A;Fleming AM;Laing RT;Town GI;Mills GD;Chambers ST;Jennings LC;;
Journal Journal of clinical microbiology
Year 2003
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12517826
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult Comparative Study Antigens DNA Evaluation Study Bacterial / analysis Polymerase Chain Reaction / methods* pneumonia streptococcus pneumoniae / genetics streptococcus pneumoniae / isolation & purification* streptococcal infections / microbiology community-acquired infections / microbiology* pneumococcal / diagnosis david r murdoch pmid:12517826 pmc149569 doi:10.1128/jcm.41.1.63-66.2003 trevor p anderson lance c jennings pneumococcal / microbiology* respiratory system / microbiology

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