Comparison of single and combination antimicrobial agents for prevention of experimental gas gangrene caused by Clostridium perfringens

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ID: 116093
1987
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Abstract
The treatment of experimental gas gangrene caused by Clostridium perfringens was investigated by using combinations of antimicrobial agents. This study demonstrated that rifampin, penicillin, metronidazole, and clindamycin were all bactericidal against standard inocula (10(5) to 10(6) CFU). These an …
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Authors Stevens DL;Laine BM;Mitten JE;;
Journal Antimicrobial agents and chemotherapy
Year 1987
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/2882732
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. female male Comparative Study microbial sensitivity tests drug therapy combination metronidazole / therapeutic use* d l stevens clindamycin / therapeutic use* j e mitten clindamycin / blood clostridium perfringens / drug effects penicillin g / blood rifampin / blood pmid:2882732 pmc174712 doi:10.1128/aac.31.2.312 b m laine gas gangrene / drug therapy* penicillin g / therapeutic use* rifampin / therapeutic use*

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