Efficacy of Vedolizumab Induction and Maintenance Therapy in Patients With Ulcerative Colitis, Regardless of Prior Exposure to Tumor Necrosis Factor Antagonists

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ID: 115945
2017
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Abstract
Vedolizumab demonstrated significantly greater efficacy as induction and maintenance therapy for UC than placebo in patients naive to TNF antagonists and patients with TNF antagonist failure. There were numerically greater treatment differences at Week 6 among patients receiving vedolizumab who were …
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Authors Feagan BG;Rubin DT;Danese S;Vermeire S;Abhyankar B;Sankoh S;James A;Smyth M;;
Journal clinical gastroenterology and hepatology : the official clinical practice journal of the american gastroenterological association
Year 2017
DOI
DOI not found
URL
https://www.pubmed.gov/27639327/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male middle aged randomized controlled trials as topic Antibodies Monoclonal Brian G Feagan Humanized / therapeutic use* Colitis Ulcerative / drug therapy* Gastrointestinal Agents / therapeutic use* placebos / administration & dosage pmid:27639327 doi:10.1016/j.cgh.2016.08.044 david t rubin michael smyth clinical trials phase iii as topic induction chemotherapy / methods maintenance chemotherapy / methods

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