Frequent genital herpes simplex virus 2 shedding in immunocompetent women. Effect of acyclovir treatment

Clicks: 378
ID: 115930
1997
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Abstract
Reactivation of herpes simplex virus type 2 (HSV-2) occurs intermittently as perceived clinically and by viral culture. We performed a series of studies to evaluate the frequency and pattern of HSV-2 reactivation using both viral isolation and HSV PCR assay. Daily samples of genital secretions were …
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Authors Wald A;Corey L;Cone R;Hobson A;Davis G;Zeh J;;
Journal The Journal of clinical investigation
Year 1997
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9062368
Keywords
Administration National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't adult female Recurrence P.H.S. Clinical Trial Antibodies Double-Blind Method DNA Viral / analysis Polymerase Chain Reaction / methods time factors controlled clinical trial pilot projects l corey antiviral agents / administration & dosage antiviral agents / therapeutic use* oral cross-over studies blotting western herpesvirus 2 a wald j zeh viral / isolation & purification herpes genitalis / virology* human / isolation & purification* acyclovir / administration & dosage acyclovir / therapeutic use* serologic tests human / drug effects immunocompetence viral / drug effects herpes genitalis / drug therapy* pmid:9062368 pmc507918 doi:10.1172/jci119237 genitalia female / virology human / growth & development sexually transmitted diseases / drug therapy* sexually transmitted diseases / virology* virus latency virus shedding*

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