Prophylactic and preventive antibiotic therapy: timing, duration and economics

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1979
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Abstract
Previous studies have demonstrated that administered antibiotics must be active against major anticipated pathogens and must have reached sufficient concentrations in the tissue or body fluid at risk by the time of bacterial challenge if prophylactic therapy is to be maximally effective in reducing …
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Authors Stone HH;Haney BB;Kolb LD;Geheber CE;Hooper CA;;
Journal annals of surgery
Year 1979
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