Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever

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ID: 114518
2002
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Abstract
Voriconazole is a suitable alternative to amphotericin B preparations for empirical antifungal therapy in patients with neutropenia and persistent fever.
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Authors Walsh TJ;Pappas P;Winston DJ;Lazarus HM;Petersen F;Raffalli J;Yanovich S;Stiff P;Greenberg R;Donowitz G;Schuster M;Reboli A;Wingard J;Arndt C;Reinhardt J;Hadley S;Finberg R;Laverdière M;Perfect J;Garber G;Fioritoni G;Anaissie E;Lee J; ;;
Journal The New England journal of medicine
Year 2002
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11807146
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male adolescent aged middle aged Child Comparative Study Prospective Studies P.H.S. 80 and over Clinical Trial Randomized Controlled Trial Multicenter Study anti-bacterial agents / therapeutic use intravenous / adverse effects fever / drug therapy* neutropenia / drug therapy* fever / etiology neutropenia / etiology chronic disease mycoses / prevention & control* neoplasms / complications antifungal agents / adverse effects pyrimidines / adverse effects triazoles / adverse effects voriconazole infusions neoplasms / therapy pmid:11807146 doi:10.1056/nejm200201243460403 thomas j walsh peter pappas national institute of allergy and infectious diseases mycoses study group amphotericin b / therapeutic use* antifungal agents / pharmacokinetics antifungal agents / therapeutic use* chemical and drug induced liver injury pyrimidines / pharmacokinetics pyrimidines / therapeutic use* triazoles / pharmacokinetics triazoles / therapeutic use*

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