Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis

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ID: 114206
1983
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Abstract
Although enterococci are relatively resistant to penicillin, the mechanism of resistance is largely unknown and enzymatic inactivation does not play a role. In this study, an isolate of Streptococcus faecalis was found to have beta lactamase activity resulting in complete inactivation of penicillin. …
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Authors Murray BE;Mederski-Samaroj B;;
Journal The Journal of clinical investigation
Year 1983
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/6411768
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine plasmids b e murray penicillins / pharmacology* penicillin resistance enterococcus faecalis / drug effects enterococcus faecalis / genetics* pmid:6411768 pmc1129285 doi:10.1172/jci111042 b mederski-samaroj enterococcus faecalis / enzymology penicillinase / biosynthesis penicillinase / metabolism* streptococcal infections / drug therapy streptococcal infections / etiology beta-lactamases / metabolism*

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