A rabbit model of intracerebral hematoma

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ID: 114043
1970
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Abstract
The epiphenomena that seem to cause deterioration and death after spontaneous interacerebral hematoma (SICH) might best be studied in an animal model. Therefore, the principles for developing such a model and techniques to study these phenomena were evaluated. Animals will tolerate injection of 3%–5% of their brain volume with a high proportion of clots. Fluorescein can be used to study the blood-brain barrier, and gravimetry to study edema. Others have found that injection of a paraffin/oil mixture can be employed for a control model. Refinement of the fluorescein technique, development of a primate model, and directions for future research are suggested.
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kaufman1970actaa Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors H. H. Kaufman;J. L. Pruessner;D. P. Bernstein;A. Borit;P. T. Ostrow;D. L. Cahall;H. H. Kaufman;J. L. Pruessner;D. P. Bernstein;A. Borit;P. T. Ostrow;D. L. Cahall;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00687015
URL
https://link.springer.com/article/10.1007/BF00687015
Keywords
pathology neurosciences

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