Cerebellar plaques in familial Alzheimer's disease (Gerstmann-Sträussler-Scheinker variant?)

Clicks: 97
ID: 114020
1970
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #380 of 438 articles by views in acta neuropathologica

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 438 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
A large kindred, with two brothers coming to autopsy, of a syndrome consisting of ataxia, dementia, and some Parkinsonian features is reported; inheritance appears to be autosomal dominant. Neuropathologically, there were plaques and neurofibrillary tangles in the cerebral cortex as well as some in the basal ganglia, particularly reminiscent of the plaques seen in Kuru; there was only minimal spinal cord disease (pyramidal tract field). The problems of classifying this condition — Alzheimer's disease with cerebellar involvement or other entities, such as the Gerstmann-Sträussler-Scheinker condition (1936), especially now that transmission to animals in the latter has been reported — are discussed. Some relevant theoretical considerations derived from animal work, particulary in scrapie, are also reviewed.
Reference Key
azzarelli1970actacerebellar Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors B. Azzarelli;J. Muller;B. Ghetti;M. Dyken;P. M. Conneally;B. Azzarelli;J. Muller;B. Ghetti;M. Dyken;P. M. Conneally;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00687003
URL
https://link.springer.com/article/10.1007/BF00687003
Keywords
pathology neurosciences

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.