Inflammatory colonic carcinogenesis: a review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis

Clicks: 350
ID: 113936
2014
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Abstract
Ulcerative colitis (UC) is characterized by repeated flare-ups of inflammation that can lead to oncogenic insults to the colonic epithelial. UC-associated carcinogenesis presents a different sequence of tumorigenic events compared to those that contribute to the development of sporadic colorectal ca …
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Authors Scarpa M;Castagliuolo I;Castoro C;Pozza A;Scarpa M;Kotsafti A;Angriman I;;
Journal world journal of gastroenterology
Year 2014
DOI
DOI not found
URL
https://www.pubmed.gov/24944468/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic review gene expression regulation humans pubmed abstract nih national institutes of health national library of medicine risk factors Colitis disease progression oxidative stress pmid:24944468 pmc4051917 doi:10.3748/wjg.v20.i22.6774 marco scarpa ignazio castagliuolo imerio angriman cell transformation neoplastic* / genetics neoplastic* / immunology neoplastic* / metabolism neoplastic* / pathology ulcerative / complications* ulcerative / genetics ulcerative / immunology ulcerative / metabolism ulcerative / pathology colonic neoplasms / etiology* colonic neoplasms / genetics colonic neoplasms / immunology colonic neoplasms / metabolism colonic neoplasms / pathology dna damage dna methylation epigenesis neoplastic inflammation mediators / metabolism neoplasm grading oncogenes t-lymphocytes / immunology t-lymphocytes / metabolism

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