Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

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ID: 112562
1993
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Abstract
Seventy-four acutely ill patients were treated with intravenous ciprofloxacin at dosages ranging between 200 mg every 12 h and 400 mg every 8 h. A population pharmacokinetic-pharmacodynamic analysis relating drug exposure (and other factors) to infectious outcome was performed. Plasma samples were o …
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Authors Forrest A;Nix DE;Ballow CH;Goss TF;Birmingham MC;Schentag JJ;;
Journal Antimicrobial agents and chemotherapy
Year 1993
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8517694
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome algorithms adult female male aged middle aged Drug Administration Schedule Prospective Studies 80 and over Clinical Trial multivariate analysis ciprofloxacin / therapeutic use ciprofloxacin / pharmacology* analysis of variance ciprofloxacin / pharmacokinetics probability pmid:8517694 pmc187901 doi:10.1128/aac.37.5.1073 a forrest d e nix j j schentag bacterial infections / drug therapy critical illness

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