Twenty-four-hour area under the concentration-time curve/MIC ratio as a generic predictor of fluoroquinolone antimicrobial effect by using three strains of Pseudomonas aeruginosa and an in vitro pharmacodynamic model
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ID: 111830
1996
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Abstract
Several investigators have suggested that the 24-h area under the concentration-time curve (AUC)/MIC ratio (AUC/MIC24 or AUIC24) can be used to make comparisons of antimicrobial activity between fluoroquinolone antibiotics. Limited data exist regarding the generic predictive ability of AUC/MIC24 for …
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| Reference Key |
kj1996antimicrobialtwenty-four-hour
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|---|---|
| Authors | Madaras-Kelly KJ;Ostergaard BE;Hovde LB;Rotschafer JC;; |
| Journal | Antimicrobial agents and chemotherapy |
| Year | 1996 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
regression analysis
microbial sensitivity tests
pseudomonas aeruginosa / drug effects*
biological
kinetics
ofloxacin / pharmacology
anti-infective agents / pharmacology*
pmid:8851583
pmc163170
doi:10.1128/aac.40.3.627
k j madaras-kelly
b e ostergaard
j c rotschafer
anti-infective agents / pharmacokinetics
ciprofloxacin / pharmacokinetics
ciprofloxacin / pharmacology
ofloxacin / pharmacokinetics
|
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