Piperacillin-tazobactam is more effective than ceftriaxone plus gentamicin in febrile neutropenic patients with hematological malignancies: a randomized comparison

Clicks: 503
ID: 111746
2003
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Abstract
Piperacillin-tazobactam monotherapy is significantly more effective and cost-efficient than ceftriaxone plus gentamicin as first-line therapy in febrile neutropenic patients with hematological malignancies.
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Authors Gorschlüter M;Hahn C;Fixson A;Mey U;Ziske C;Molitor E;Horré R;Sauerbruch T;Marklein G;Schmidt-Wolf IG;Glasmacher A;;
Journal Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Year 2003
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12690546
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male adolescent aged middle aged 80 and over Clinical Trial Randomized Controlled Trial drug therapy combination fever / drug therapy* gentamicins / administration & dosage anti-bacterial agents / pharmacology* neutropenia / drug therapy* anti-bacterial agents / administration & dosage fever / etiology neutropenia / etiology penicillins / pharmacology* enzyme inhibitors / administration & dosage pmid:12690546 doi:10.1007/s00520-003-0463-7 m gorschlüter c hahn a glasmacher anti-bacterial agents / economics ceftriaxone / administration & dosage ceftriaxone / economics ceftriaxone / pharmacology* cost-benefit analysis enzyme inhibitors / economics enzyme inhibitors / pharmacology* gentamicins / economics gentamicins / pharmacology* hematologic neoplasms / complications penicillanic acid / administration & dosage penicillanic acid / analogs & derivatives* penicillanic acid / economics penicillanic acid / pharmacology* penicillins / administration & dosage penicillins / economics piperacillin / administration & dosage piperacillin / economics piperacillin / pharmacology* tazobactam

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