Detection of Streptococcus pneumoniae Antigen in Bronchoalveolar Lavage Fluid Samples by a Rapid Immunochromatographic Membrane Assay

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ID: 111517
2005
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Abstract
We conducted a retrospective study to evaluate an immunochromatographic membrane test (ICT), applied to bronchoalveolar lavage (BAL) fluid samples obtained in patients with suspected pneumonia, for the detection of Streptococcus pneumoniae antigen. The NOW Streptococcus pneumoniae test was assessed on 96 BAL fluid samples. Sensitivity was tested in 20 samples obtained from patients diagnosed as having pneumococcal pneumonia (growth of S. pneumoniae in blood cultures and/or in BAL fluid samples of ≥104 CFU/ml). Specificity was tested in BAL fluid samples of nonpneumococcal etiology ( n = 41) and in samples with no respiratory pathogen and a total bacterial count of
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Authors Jan A. Jacobs;Ellen E. Stobberingh;Elisa I. M. Cornelissen;Marjolein Drent;Jan A. Jacobs;Ellen E. Stobberingh;Elisa I. M. Cornelissen;Marjolein Drent;
Journal Journal of clinical microbiology
Year 2005
DOI
10.1128/JCM.43.8.4037-4040.2005
URL
http://dx.doi.org/10.1128/JCM.43.8.4037-4040.2005
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult female male aged middle aged Retrospective Studies Antigens bacterial / analysis* streptococcus pneumoniae / immunology* pmid:16081947 pmc1233991 doi:10.1128/jcm.43.8.4037-4040.2005 jan a jacobs ellen e stobberingh marjolein drent bronchoalveolar lavage fluid / microbiology* chromatography / methods*

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