Juvenile Parkinson's disease with widespread Lewy bodies in the brain

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ID: 111128
1970
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Abstract
A clinico-pathological case report on a case of juvenile Parkinson's disease (JPD) with widespread Lewy bodies (LBs) in the brain is presented with comparative morphological studies on two demented cases of “classical” Parkinson's disease (CPD) with disease onset at an older age. The clinical and histological pictures of this JPD case were typical of Parkinson's disease, excepting numerous Lewy bodies in the cerebrum. There were no neurofibrillary change nor senile plaques throughout the CNS. The distribution and histochemical and ultrastructural characters of the histological lesions (i.e., LBs) in the JPD and the two CPD cases were investigated and compared. The comparison showed no qualitative but only quantitative differences between the two types of Parkinson's disease. The present study also revealed that in CPD cases significant numbers of LBs could be present in the cerebral cortex, amygdaloid and claustrum. These lesions can be in part responsible for dementia in CPD.
Reference Key
yoshimura1970actajuvenile Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors N. Yoshimura;I. Yoshimura;M. Asada;S. Hayashi;Y. Fukushima;T. Sato;H. Kudo;N. Yoshimura;I. Yoshimura;M. Asada;S. Hayashi;Y. Fukushima;T. Sato;H. Kudo;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00687434
URL
https://link.springer.com/article/10.1007/BF00687434
Keywords
pathology neurosciences

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