Elektronenoptische und enzymhistochemische Vergleichsuntersuchungen an Kraniopharyngiomen und ihren Gewebekulturen

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ID: 110742
1970
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Abstract
Electron optical and enzyme histochemical investigations carried out on four craniopharyngiomas and their tissue cultures demonstrated that the tumour elements are keratinizing epithelial cells, plenty of tonofilaments, glycogen granules, mitochondria and desmosomes. Their ultrastructural and histochemical characteristics are the same in every part of the tumour (solid; cystic; “adamantinoma-like”). In the keratinizing cells, the reactions for non-specific esterases were high positive. The ultrastructural characteristics of the tumour cells grownin vitro are the same as thosein situ; the cells remain attached to one another by desmosomes and retain their capacity to produce keratine. This therefore seems to be a primary characteristic of the tumour cells and not a secondary dysmetabolic disturbance. Calcium was found onlyin situ. That the tumour cells may produce enamelin situ seems to be possible, but it could not be confirmed with certainty. The glial proliferation which is always presentin situ, is reactive and not neoplastic; thein vitro new built cell colonies consist only of epithelial elements.
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genth1970actaelektronenoptische Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors J. Genth;F. Gullotta;J. Puig Serra;J. Genth;F. Gullotta;J. Puig Serra;
Journal acta neuropathologica
Year 1970
DOI
doi:10.1007/BF00685287
URL
https://link.springer.com/article/10.1007/BF00685287
Keywords
pathology neurosciences

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