A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia

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ID: 110706
1986
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Abstract
To assess the efficacy of single-agent therapy relative to standard combination antibiotic therapy for the initial management of fever and neutropenia in cancer patients, we conducted a randomized trial comparing ceftazidime alone with a combination of cephalothin, gentamicin, and carbenicillin. Of …
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Authors Pizzo PA;Hathorn JW;Hiemenz J;Browne M;Commers J;Cotton D;Gress J;Longo D;Marshall D;McKnight J;;
Journal The New England journal of medicine
Year 1986
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/3526155
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE clinical trials as topic humans pubmed abstract nih national institutes of health national library of medicine adult female male adolescent aged middle aged Child Drug Administration Schedule Recurrence Comparative Study Prospective Studies preschool Clinical Trial Randomized Controlled Trial Random Allocation anti-bacterial agents / adverse effects pmid:3526155 doi:10.1056/nejm198608283150905 p a pizzo j w hathorn j mcknight agranulocytosis / complications* anti-bacterial agents / administration & dosage* bacterial infections / prevention & control* carbenicillin / administration & dosage ceftazidime / administration & dosage ceftazidime / adverse effects ceftazidime / therapeutic use* cephalothin / administration & dosage drug therapy combination fever / drug therapy* fever of unknown origin / drug therapy gentamicins / administration & dosage neoplasms / complications* neutropenia / complications* sepsis / prevention & control

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