The ultrastructure of myelin and axonal alterations in sciatic nerves of thiamine deficient and chronically starved rats

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ID: 110562
2016
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Abstract
Phase and electron microscopic study of sciatic and peroneal nerves of thiamine deficient and chronically starved rats demonstrated an increase in the incidence of normal variations in myelin sheath contour throughout the internode, focal alterations in the lamellar pattern of myelin adjacent to sites of demyelination, and numerous, complex, redundant loops of axon-Schwann cell membrane which projected into axons of myelinated fibers. The paranodal axoplasm of a few fibers from thiamine deficient rats contained collections of vesicles, mitochondria and dense bodies. The significance of these observations is briefly discussed.
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collins2016actathe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors George H. Collins;Henry de F. Webster;Maurice Victor;George H. Collins;Henry de F. Webster;Maurice Victor;
Journal acta neuropathologica
Year 2016
DOI
doi:10.1007/BF00688459
URL
https://link.springer.com/article/10.1007/BF00688459
Keywords
pathology neurosciences

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