The Effects of Adding Transcutaneous Spinal Cord Stimulation (tSCS) to Sit-To-Stand Training in People with Spinal Cord Injury: A Pilot Study

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ID: 110415
2020
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Abstract
Spinal cord stimulation may enable recovery of volitional motor control in people with chronic Spinal Cord Injury (SCI). In this study we explored the effects of adding SCS, applied transcutaneously (tSCS) at vertebral levels T10/11, to a sit-to-stand training intervention in people with motor complete and incomplete SCI. Nine people with chronic SCI (six motor complete; three motor incomplete) participated in an 8-week intervention, incorporating three training sessions per week. Participants received either tSCS combined with sit-to-stand training (STIM) or sit-to-stand training alone (NON-STIM). Outcome measures were carried out before and after the intervention. Seven participants completed the intervention (STIM N = 5; NON-STIM N = 2). Post training, improvements in International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) motor scores were noted in three STIM participants (range 1.0–7.0), with no change in NON-STIM participants. Recovery of volitional lower limb muscle activity and/or movement (with tSCS off) was noted in three STIM participants. Unassisted standing was not achieved in any participant, although standing with minimal assistance was achieved in one STIM participant. This pilot study has shown that the recruitment of participants, intervention and outcome measures were all feasible in this study design. However, some modifications are recommended for a larger trial.
Reference Key
al’joboori2020journalthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yazi Al’joboori;Sarah J. Massey;Sarah L. Knight;Nick de N. Donaldson;Lynsey D. Duffell;Al’joboori, Yazi;Massey, Sarah J.;Knight, Sarah L.;Donaldson, Nick de N.;Duffell, Lynsey D.;
Journal journal of clinical medicine
Year 2020
DOI
10.3390/jcm9092765
URL
https://doi.org/10.3390/jcm9092765##related
Keywords
neuromodulation human spinal cord injury non-invasive neurorehabilitation transcutaneous spinal cord stimulation National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine pmid:32858977 doi:10.3390/jcm9092765 yazi al'joboori sarah j massey lynsey d duffell

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