Nitric oxide as a source for bacterial triazole biosynthesis
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ID: 110369
2020
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Abstract
How nature creates 1,2,3-triazole ring is a relevant question to N-N bond biosynthesis. Here, the authors report the biosynthetic route to the triazole-bearing antimetabolite 8-azaguanine and reveal that this can be assembled through an enzymatic and non-enzymatic cascade, in which nitric oxide is used as a building block.
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zhao2020nitricnature
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| Authors | Zhao, Guiyun;Guo, Yuan-Yang;Yao, Shunyu;Shi, Xinjie;Lv, Longxian;Du, Yi-Ling; |
| Journal | Nature communications |
| Year | 2020 |
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