Extensive identification and analysis of conserved small ORFs in animals

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ID: 110036
2015
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Abstract
Taken together, we identify hundreds of previously unknown conserved sORFs in major model organisms. Our computational analyses and integration with experimental data show that these sORFs are expressed, often translated, and sometimes widely conserved, in some cases even between vertebrates and inv …
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Authors Mackowiak SD;Zauber H;Bielow C;Thiel D;Kutz K;Calviello L;Mastrobuoni G;Rajewsky N;Kempa S;Selbach M;Obermayer B;;
Journal Genome biology
Year 2015
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/26364619
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't pmid:26364619 pmc4568590 doi:10.1186/s13059-015-0742-x sebastian d mackowiak henrik zauber benedikt obermayer 3' untranslated regions amino acid motifs amino acid sequence codon terminator conserved sequence exons open reading frames* peptides / chemistry protein biosynthesis sequence alignment bioinformatics evolutionary biology animal genetics and genomics microbial genetics and genomics plant genetics and genomics human genetics

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