Global analysis of clinical trials with probiotics.

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ID: 109328
2020
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Abstract
Over 1,000 clinical studies with probiotics, registered at ClinicalTrials.gov and/or the International Clinical Trials Registry Platform (ICTRP) of the World Health Organization, have addressed over 700 different diseases and conditions. The average size of a clinical trial with probiotics (74 participants) is comparable to the overall average of all studies in ClincialTrials.gov. GG (LGG) and ssp. BB12 are the probiotic strains studied most. The exact composition of the product which is used, including the dosage, is not always indicated in the registry. The majority of probiotics studies at ClinicalTrials.gov is registered in the USA or Europe (56%). The data from ICTRP show the rapid expansion of clinical studies with probiotics in Asia, notably Iran and China.
Reference Key
dronkers2020globalheliyon Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Dronkers, Theresia M G;Ouwehand, Arthur C;Rijkers, Ger T;
Journal Heliyon
Year 2020
DOI
10.1016/j.heliyon.2020.e04467
URL
Keywords
microorganism bacteria clinical trials prebiotics immune system microbiota probiotics immunology digestive system

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