Could autism spectrum disorders be a risk factor for COVID-19?

Clicks: 230
ID: 107406
2020
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Abstract
The coronavirus SARS-CoV-2 pandemia is infecting millions of people and some studies relate conditions that might increase the risk of developing a fatal course for the disease, such as diabetes, cardiovascular diseases and obesity. In COVID-19 physiopathology, one of the main inflammation mechanisms is the "cytokine storm", causing a pro-inflammatory state, related to cardiac and pulmonary damage. There is also a less effective role of lymphocyte B and T in the humoral immunity due to the reduction of their proliferative response. The physiopathology of ASD (Autism Spectrum Disorder) involves several modifications at the genetic and at the immune level, such as the increase of inflammatory cytokines and abnormal immune response in several levels. We hypothesize that ASD could be a risk-factor as the other conditions are.
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lima2020couldmedical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lima, Matheus Eugênio de Sousa;Barros, Levi Coelho Maia;Aragão, Gislei Frota;
Journal medical hypotheses
Year 2020
DOI
S0306-9877(20)31071-9
URL
Keywords
coronavirus autism spectrum disorder risk factor covid-19 sars-cov-2

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