Nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome.

Клики: 260
ID: 276031
2022
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Аннотация
Obesity and metabolic disorders represent a significant global health problem and the gut microbiota plays an important role in modulating systemic homeostasis. Recent evidence shows that microbiota and its signaling pathways may affect the whole metabolism and the Renin-Angiotensin System (RAS), which in turn seems to modify microbiota. The present review aimed to investigate nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome components. A description of metabolic changes was obtained based on relevant scientific literature. The molecular and physiological mechanisms that impact the human microbiome were addressed, including the gut microbiota associated with obesity, diabetes, and hepatic steatosis. The RAS interaction signaling and modulation were analyzed. Strategies including the use of prebiotics, symbiotics, probiotics, and biotechnology may affect the gut microbiota and its impact on human health.
Ссылочный ключ
guimares2022nutritionalthe Используйте этот ключ для автоцитирования в рукописи при использовании SciMatic Manuscript Manager или Thesis Manager
Авторы Guimarães, Victor Hugo Dantas;Marinho, Barbhara Mota;Motta-Santos, Daisy;Mendes, Gabriela da Rocha Lemos;Santos, Sérgio Henrique Sousa;
Журнал The Journal of nutritional biochemistry
Год 2022
DOI
10.1016/j.jnutbio.2022.109252
URL
Ключевые слова
obesity nutrition metabolic syndrome gut microbiota renin-angiotensin system microbial therapy

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