effect of 8 weeks resistance training on bdnf and trkb in the hippocampus of adult male rats

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ID: 181943
2014
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Resumo
Background & aim: Exercise enhances the synaptic plasticity and neuroprotective effects in the adult brain. However, it remains unknown that how plasticity molecules change following types of training. The purpose of this study was to determine the effect of eight weeks resistance training on protein levels of Brain Derived Neurotrophic Factor(BDNF) and receptor of TrkB, in the hippocampus of adult male rats. Methods: In this experimental study, twelve adult male rats, 8 weeks of age, with an average weight of 200 to 225 grams were randomly divided into two groups, control and exercise respectively. The exercise was to increase the weight on the ladder. 24 hours after their last training session. The animals were killed and the hippocampus was removed for further testing. ELISA determined changes in protein levels. Data were analyzed by independent t test. Results: There was a significant difference between train and control groups In protein level of variables statically (p≤0.05). In addition, protein levels of BDNF and TrkB in the hippocampus of rats increased. Conclusion: Resistance training is beneficial for promoting hippocampal plasticity associated with BDNF signaling and consequently functional and cognitive benefits.
Chave de Referencia
mojtahedi2014armaghaneeffect Use esta chave para citacao automatica no manuscrito ao usar SciMatic Gerenciador de Manuscritos ou Gerenciador de Teses
Autores ;S Mojtahedi;F Shabkhiz;A Akbarnejad;O Salehian
Periodico korean journal of food preservation
Ano 2014
DOI
DOI nao encontrado
URL
http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-72&slc_lang=en&sid=1
Palavras-chave
Medicine (General) resistance training Hippocampus elisa

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