repeat contractions

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Large-scale contractions of Friedreich's ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability.
Khristich, Alexandra N;Armenia, Jillian F;Matera, Robert M;Kolchinski, Anna A;Mirkin, Sergei M;
2020 Proceedings of the National Academy of Sciences of... DOI: 10.1073/pnas.1913416... 252 views

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dna replication friedreich’s ataxia dna triplex repeat expansion diseases