A novel, heterogeneous and recyclable polymeric catalyst for the one-pot synthesis of polyhydroquinoline and 1,8-dioxohexahydroacridine derivatives under solvent-free conditions.

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2012
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Abstract
An efficient, recyclable and environmental-friendly synthetic route to polyhdroquinoline and 1,8-dioxohexahydroacridine derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with (a) cyclic 1,3-dicarbonyl compounds and ethyl acetoacetate, and (b) 2 equivalents of cyclic 1,3-dicarbonyl compounds in the presence of novel polymeric catalyst [poly(AMPS-co-AA)] under solvent-free conditions. The present approach offers several advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.
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maleki2012aacta Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Maleki, Behrooz;Tayebee, Reza;Sepehr, Zeinalabedin;Kermanian, Mina;
Journal acta chimica slovenica
Year 2012
DOI
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Keywords
Antimicrobial activity multicomponent reaction antimalarial activity 5-imidazopyrazole incorporated polyhydroquinolines antituberculosis activity

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