StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.

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ID: 97084
2020
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Abstract
Population genetics focuses on the analysis of genetic differences within and between-group of individuals and the inference of the populations' structure. These analyses are usually carried out using Bayesian clustering or maximum likelihood estimation algorithms that assign individuals to a given population depending on specific genetic patterns. Although several tools were developed to perform population genetics analysis, their standard graphical outputs may not be sufficiently informative for users lacking interactivity and complete information. StructuRly aims to resolve this problem by offering a complete environment for population analysis. In particular, StructuRly combines the statistical power of the R language with the friendly interfaces implemented using the shiny libraries to provide a novel tool for performing population clustering, evaluating several genetic indexes, and comparing results. Moreover, graphical representations are interactive and can be easily personalized. StructuRly is available either as R package on GitHub, with detailed information for its installation and use and as shinyapps.io servers for those users who are not familiar with R and the RStudio IDE. The application has been tested on Linux, macOS and Windows operative systems and can be launched as a shiny app in every web browser.
Reference Key
criscuolo2020structurlyplos Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Criscuolo, Nicola G;Angelini, Claudia;
Journal PloS one
Year 2020
DOI
10.1371/journal.pone.0229330
URL
Keywords
sleep genetics high-throughput phenotyping diversity outbred mice circadian period modified murine multiple sleep latency test sleep latency in new environment

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