Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage

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ID: 96427
2018
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Abstract
Inner ear hair cells are mechanosensory receptors that perceive mechanical sound and help to decode the sound in order to understand spoken language. Exposure to intense noise may result in the damage to the inner ear hair cells, causing noise-induced hearing loss (NIHL). Particularly, the outer hair cells are the first and the most affected cells in NIHL. After acoustic trauma, hair cells lose their structural integrity and initiate a self-deterioration process due to the oxidative stress. The activation of different cellular death pathways leads to complete hair cell death. This review specifically presents the current understanding of the mechanism exists behind the loss of inner ear hair cell in the auditory portion after noise-induced trauma. The article also explains the recent hair cell protection strategies to prevent the damage and restore hearing function in mammals.
Reference Key
waqas2018innerneural Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Waqas, Muhammad;Gao, Song;Iram-us-Salam, ;Ali, Muhammad Kazim;Ma, Yongming;Li, Wenyan;
Journal neural plasticity
Year 2018
DOI
DOI not found
URL
http://dx.doi.org/10.1155/2018/3170801
Keywords
Medicine (General) Medicine Science otorhinolaryngology neurosciences. biological psychiatry. neuropsychiatry philology. linguistics industrial medicine. industrial hygiene

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