Successful treatment of ulcerative necrobiosis lipoidica with JAK inhibitor.
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2020
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Abstract
Necrobiosis lipoidica (NL) is a rare granulomatous disease that predominantly affects middle aged women and is often associated with diabetes mellitus and other metabolic disorders . About 30 % of the patients develop ulcerations within NL lesions on the lower leg, which complicate the course of disease and are often recalcitrant to standard wound care procedures . Systemic therapies for NL are reported only for single cases or in small case series with varying outcome . Randomized controlled trials are missing due to the character of NL as an orphan disease.
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| Authors | Erfurt-Berge, C;Sticherling, M; |
| Journal | journal of the european academy of dermatology and venereology : jeadv |
| Year | 2020 |
| DOI |
10.1111/jdv.16297
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